All cigarettes contained at least one allergenic flavoring agent regardless of the inclusion of flavoring capsules. Here, we developed and validated a simultaneous analysis method for 25 allergenic flavoring agents and menthol with gas chromatography–tandem mass spectrometry to determine levels of flavoring agents in the tobacco, filter tips, and capsules of 54 commercial cigarettes in Korea. Moreover, no studies have assessed the risk of adding allergenic flavoring agents in cigarettes. Previous studies have investigated the levels of flavoring agents in tobacco but none has focused on their content in filter tips and capsules. ![]() ![]() There are mostly permitted food additives, but some of them are restricted for use in food, cosmetics, and toys, since they can cause allergic reactions. Flavoring agents are added to cigarettes to improve taste.
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